EPA Method 1666


EPA Method 1666 does not directly match ALS - Columbia's list of currently available methods. Please call for availability.


Method information displayed is provided for informational purposes only. No warranty (express or implied) is made as to the website accuracy, completeness, or applicability (such as the age of a method and whether or not it applies to your project). Please contact us for assistance. Analytical testing dots

PDF IconView Actual EPA Method 1666 (PDF File)


EPA Method 1666:
Volatile Organic Compounds Specific to the Pharmaceutical Manufacturing Industry by Isotope Dilution GC/MS

Summary:
Stable, isotopically labeled analogs of the compounds of interest are added to the sample and the sample is purged with an inert gas at 45EC in a chamber designed for soil or water samples, as appropriate. In the purging process, the volatile compounds are transferred from the aqueous phase into the vapor phase, where they are passed into a sorbent column and trapped. After purging is completed, the trap is backflushed and heated rapidly to desorb the compounds into a gas chromatograph (GC). The compounds are separated by the GC and detected by a mass spectrometer (MS).

Scope:
This method is for surveying and monitoring under the Clean Water Act. It is used to determine certain volatile organic pollutants specific to the pharmaceutical manufacturing industry (PMI) that are amenable to purge-and-trap gas chromatography/mass spectrometry (GC/MS) or direct aqueous injection GC/MS.

Report Number:
821/B-94-001

Analytical testing dots


Examples:  8260
TO-15

Examples:  Dioxin
Mercury
Analytical testing dots


<-- Search All Test Methods



Suggestions? The test methods page continues to expand and improve. If you have suggestions for improvement, we would enjoy hearing from you. Please contact the webmaster here.


Analytical testing dots