Aflatoxin Testing Using LC/MS/MS Offered by Columbia Analytical
Columbia Analytical Services announces their analysis of the B1, B2 and G1, G2 aflatoxins via liquid chromatography/mass spectroscopy/mass spectroscopy (LC/MS/MS).
Aflatoxins are potent natural carcinogens produced by the fungi Aspergillus flavus or Aspergillus parasiticus. These fungi are known to grow on nuts, spices, milk, oilseed cereals and other agricultural products as well as in water damaged carpets. Aflatoxins have also been found in medicinal herbs contaminated by fungi. Aflatoxins have been classified as group 1 carcinogens by the International Agency for Research on Cancer (IARC).The European Commission have set 4 μg/Kg limits for maximum total aflatoxin content in products for direct human consumption.
“Traditionally quantization of aflatoxins have been performed using thin layer chromatography, or more recently, liquid chromatography with fluorescence detection (HPLC/FD),” said Dr. Ewan Sinclair, Scientist for Columbia Analytical. “However, LC/MS/MS provides greater sensitivity and selectivity necessary for trace analysis of aflatoxins in complex food matrices.”
Columbia Analytical has developed special prep procedures for complex food matrices followed by LC/MS/MS for the analysis of these selected aflatoxins. Using this prep and analytical approach Columbia Analytical is able to achieve method reporting limits (MRL) of 2 μg/kg for aflatoxins B1 and G1, and 1 μg/kg for aflatoxins B2 and G2.
For more information on aflatoxins and LC/MS/MS technology contact Columbia Analytical online at http://www.caslab.com/Aflatoxin-Testing/ or call 360-577-7222.