Comments on: Anthraquinone Analysis Offered by Columbia Analytical

By: Princess

Princess — Tue, 03 Apr 2012 02:46:38 +0000

Pls, I want to know the aim of these experiment.

By: Mimie

Mimie — Tue, 28 Feb 2012 17:14:13 +0000

Hi Prak1020USP eahimspze to MERELY verify the compendial method on actual condition of use. Determining the appropriate parameters to establish the efficacy of compendial test methods can be confusing especially when performed using a particular lab?s analysts, instrumentation, and supplies. Moreover, the requirements for method verification are not well defined. The Current Good Manufacturing Practice (cGMP) regulations include a requirement to verify the suitability of testing methods under actual conditions of use, as listed in 21 CFR 211.194(a)(2). Although this is a long-standing part of the regulations, the meaning of this section is difficult to interpret. Like so many of the cGMP requirements, the expectations of the industry with regard to method verification have evolved over time. So simply it can be decide to have Ruggedness for method transferation then what is the use or benifit of the Compendial method.USP recently proposed a new general information chapter, Verification of Compendial Procedures, to clarify guidelines for ensuring that a compendial method will give acceptable results. Although transfer protocols and method validation for finished products and active pharmaceutical ingredients are common in the contract laboratory setting, it is much less common to apply these same detailed principles to compendial methods on inactive ingredients or excipients. The proposed chapter recommends verification of tests that use liquid chromatography, gas chromatography, spectrophotometric, titrimetric, and thin-layer chromatography techniques. Verification is not required for USP general chapter tests, such as residue on ignition , pH, and heavy metals . Microbiological procedures are also excluded from the proposal because they are covered in other USP chapters. Method verification typically includes a subset of the parameters evaluated when a complete validation is performed. Precision, specificity, and detection limit are among the characteristics checked when verifying a compendial method. No matter what parameters are to be verified, the study should proceed according to an approved protocol that defines the characteristics to be evaluated and sets acceptance criteria to be used in judging the results of the study. Data from a method verification study should be summarized in a final report that will serve as documentation of the lab?s ability to achieve reliable results for a given test. Also check out very good discussion on the same

By: Rebecca Templado

Rebecca Templado — Fri, 02 Sep 2011 03:32:08 +0000

Sir,

I would like to know if you procedure for the testing of residual Anthraquinone in pulp. If you have can you provide one. Thank you.

By: Columbia Analytical

Columbia Analytical — Thu, 03 Jun 2010 00:07:28 +0000

Hello Toulack!

We test samples for anthraquinone on a routine basis by NCASI Method AQ-S108-01, however, we are not at liberty to discuss our data results. I am not aware of published studies of anthraquinone analyses. For more information you might try contacting NCASI.

By: Toulack Kingsley

Toulack Kingsley — Wed, 02 Jun 2010 09:25:00 +0000

sir, i would like to know recent tests for anthroquinones other than that of Harbone in 1976.

By: Columbia Analytical

Columbia Analytical — Mon, 18 Jan 2010 17:09:33 +0000

You may contact the ISO organization directly for this information. Their website may be found at http://www.iso.org. The Technical Association of Pulp and Paper Industries (www.TAPPI.org) organization may also be helpful. We do perform a number of the tests for coatings/paper/etc. based on industry methods, but the actual procedures we use are proprietary to our company.

By: muthu

muthu — Mon, 18 Jan 2010 08:28:00 +0000

dear sir
i want to know about the analytical methodology for testing the coating paper and board. i would like to thank if you have send the ISO procedure for the analytical method of quality testing paper and board.
thanking you

By: Columbia Analytical

Columbia Analytical — Tue, 20 Oct 2009 10:40:44 +0000

We use a method from the National Council of Air and Stream Improvement (NCASI) - Method AQ-S108.01, a GC/MS procedure. We cannot give those methods out, but you can request a copy of the method from them. As to exactly how we perform the method in our laboratories - that information is proprietary to our company.

In response to the request for common plants with anthraquinones, I would suggest you search the internet or contact a local University’s botany department. We do not have such a list. If you would like Columbia Analytical to perform this tests for you, please contact Ed Wallace or Jeff Christian at 360-577-7222. Thank you!

By: Kamalha Edwin

Kamalha Edwin — Fri, 16 Oct 2009 11:43:46 +0000

Thank you for the information. Please may you avail with comprehensive data on
-Test for anthraquinones in plants
-Extraction of anthaquinones from plants
-Purification of anthraquinones from plants
-Common plants with anthraquinones (botanical and common names)

By: rawy

rawy — Thu, 15 Oct 2009 13:58:45 +0000

I want to know how can i test anthraquinon in exacted plant