Columbia Analytical Tucson Laboratory is excited to announce the arrival of their new LECO TruSpec Carbon, Hydrogen, Nitrogen, Sulfur (CHNS) Analyzer with Oxygen Module and Auto Samplers.

The addition of this new equipment will enable Columbia Analytical to increase capacity for CHNS analyses and analyze difficult matrices for oxygen.

“We can analyze CHNS on a single aliquot of sample, thus reducing the amount of the sample needed. Oxygen analyses can also be performed on organo-metallic samples and samples containing fluorine,” stated Lab Manager Ralph Poulsen. “The instrument is easily switched from CHNS to oxygen and stabilizes within an hour versus up to a day with other instruments.”

TruSpec analyzers operate at a higher pyrolysis temperature (1,250 vs 950C) which is critical in breaking organo-metallic and oxygen bounds and it uses IR detectors which eliminates the need for a gas separation column that is easily poisoned by low concentrations of fluorine in the sample.

“Oxygen analyses times will be greatly improved from approximately five to six minutes to less than two minutes,” said Poulsen. “This new analyzer also supports compliance to FDA Regulation 21 CFR Part 11 and AOAC, AACC, AOCS, ASBC and ASTM approved methods of analyses.”

For more information on micro-elemental testing, contact Ralph Poulsen, Columbia Analytical Services, Inc. at 520-573-1061 or visit their website at www.caslab.com.

The CAS - Kelso laboratory is cGMP compliant and registered with the FDA. CAS’ comprehensive quality assurance and ethics programs ensure that data produced is scientifically sound, legally defensible, and accurately documented. To ensure that your analytical needs are met, your project is managed by one of our in-house project chemists. Our capabilities, expertise, and services include the following:

Monograph Testing – USP/NF, EP, JP, and BP monograph testing. This includes raw material and final product testing. An example of this includes Organic Volatile Impurities testing by USP <467>. CAS can also complete testing using client supplied methodology.

Method Development and Validation – Our professional scientists have extensive experience in analytical chemistry and can assist in method development and validation for pharmaceutical testing. Methods are validated to current ICH and USP guidelines.

Engineering Studies/Process Validation – Scientists at CAS are accustomed to non-routine testing and have the knowledge and resources to solve your analytical problems. Examples of this include analytical support for cleaning studies or manufacturing processes.

Stability Testing – CAS provides analytical support to your stability study testing. This may include assay testing, physical testing, and impurity and degradation product monitoring. This also includes development and validation of stability indicating assays.

CAS has extensive instrumental testing capabilities. CAS’ general analytical capabilities include the following: Karl Fischer, Gas Chromatography, Gas Chromatography/Mass Spectrometry, High- Performance Liquid Chromatography, Inductively Coupled Plasma/Mass Spectrometry, Inductively Coupled Plasma/ Atomic Emission Spectroscopy, Atomic Absorption, LC/MS/MS (currently being installed), and many general chemistry techniques.

Our services will help to keep your turn-around-times ahead of schedule, costs under budget, and most importantly meet cGMP quality and regulatory requirements.

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